http://localhost:8080/xmlui/handle/123456789/381 Sun, 31 May 2026 10:23:54 GMT 2026-05-31T10:23:54Z http://localhost:8080/xmlui/handle/123456789/1221 Title: Development, Characterization and Evaluation of Mesalamine Loaded Probiotic Based Microcarriers for the Management of Ulcerative Colitis Authors: Singh, Amandeep Sun, 01 Jan 2023 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/1221 2023-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/880 Title: Development and Evaluation of Some Novel Formulations for Efficient Delivery of Cholecalciferol Authors: Rawat, Neha; Supervisor: Baldi, Ashish Mon, 01 Jan 2024 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/880 2024-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/879 Title: Intensifying Solubility and Bioavailability of Arteether through Molecular Encapsulation based Oral Drug Delivery System Authors: Neha; Supervisor: Baldi, Ashish Sun, 01 Jan 2023 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/879 2023-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/837 Title: Development Characterization and Evaluation of Mesalamine Loaded Probiotic Based Microcarriers for the Management of Ulcerative Colitis Authors: Amandeep Singh; Supervisor: Narang, Raj Kumar and Mandal Uttam Kumar Abstract: To manage UC, promising colonic drug delivery systems of Mesalamine and S. boulardii were developed. The developed pectin-based microparticles and pellets containing Mesalamine and S. boulardii were coated with CAP so premature drug and probiotic release in the stomach and small intestine can be minimized. The prepared drug delivery systems can also release the drug and probiotics in the specific colon-inflamed site. We demonstrated that the prepared coated microparticles and pellets containing Mesalamine and S. boulardii could decrease the level of LPO and MPO in colitis and increase GSH. The improvement in stool consistency and macroscopic scores ensured that the combination of Mesalamine with S. boulardii significantly benefits the TNBS colitis model in Wistar rats. The S. boulardii shows additive effects when given with Mesalamine. The altered probiotic concentration in UC might be maintained by using the probiotic. The study showed that the CAP-coated microparticles and pellets containing Mesalamine and S. boulardii have better therapeutic efficacy and reduce the side effects of the drug by loading it in a suitable drug carrier. Sun, 01 Jan 2023 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/837 2023-01-01T00:00:00Z